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KMID : 0380019950100020113
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Korean Journal of Biotechnology and Bioengineering
1995 Volume.10 No. 2 p.113 ~ p.118
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Optimized Production of Microbial Surfactant, S-acid, from Penicilium spiculisporum
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Abstract
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Investigation and optimization of culturing conditions were performed for the production of microbial surfactant, 0-acid (precursor of S-acid) using Penicilium spiculisporum. Glucose and ammonium nitrate were found to be the most effective carbon and nitrogen sources, respectively. Supplementation of medium with trace elements, such as CaCIZ and FeSO4, increased the 0-acid production by 20% and maintenance of the dissolved oxygen tension near saturation increased 40% of the 0-acid productivity. Also 60% increase in the 0-acid production was observed by maintaining the glucose concentration near 50g/l by feeding glucose during the cultivation.
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